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Released in 2001 by Nintendo, Dr. Mario 64 is a puzzle game featuring Mario as a doctor. Players match colored pills with viruses to clear them from the screen. The game is praised for its addictive gameplay and multiplayer modes.

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Gameplay of Dr. Mario 64 (USA)
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Screenshot of Dr. Mario 64 (USA)
Logo of Dr. Mario 64 (USA)
Screenshot of Dr. Mario 64 (USA)

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